Repeat Microdissection Testicular Sperm Extraction in Azoospermic Men with Nonmosaic Klinefelter Syndrome

Introduction. To investigate the predictive factors for successful repeat microdissection testicular sperm extraction attempts in patients with Klinefelter syndrome. Methods. A total of 28 azoospermic men nonmosaic syndrome who have received twice initial our institute were studied. Outcome variables (age, serum follicle-stimulating hormone, luteinizing testosterone, prolactin, and estradiol) a 2nd surgical retrieval attempt (group A) compared to those an unsuccessful B). Results. Twenty-one (75%) had recovery at attempt. The mean testosterone level baseline before 1st was higher group than B (2.7 vs. 0.9 ng/mL, p < 0.01 , 3.9 1.1 id="M2"> = 0.02 ). Receiver operating characteristic curve analysis identified threshold concentration (1.5 ng/mL) predicting revealed positive negative values 94.44% 60%, respectively. Conclusion. Azoospermic presenting low levels during first procedure are unlikely retrieve on Hence, these should be properly counseled retrieval.